ANTIOXIDANT STATUS OF ORGANISM AFFECTED BY DECIMETER ELECTROMAGNETIC RADIATION DURING VARIOUS PERIODS OF PRENATAL DEVELOPMENT

Abstract

The article presents the results of studying the effect of exposure to high-frequency non-ionizing electromagnetic radiation in the embryonic and fetal periods of prenatal development on the activity of antioxidant enzymes in early postnatal ontogenesis. The study used a physiotherapy device "Volna-2", emitting in the UHF frequency range of 460 MHz. According to the results obtained, the activity of catalase and superoxide dismutase enzymes in 20- and 30-day old rats from mothers exposed to radiation during the embryonic period of prenatal development significantly increases compared to the control. At the same time, offspring from mothers exposed to radiation in the fetal period of intrauterine development have a decrease in the activity of the catalase enzyme at the same age groups, while the activity of the superoxide dismutase enzyme shows an increased level in relation to control animals. A pro-oxidant-antioxidant study of homeostasis under the influence of electromagnetic raditaion showed that in early ontogenesis, namely in 20- and 30 day-old rats, there is an increase in the activity of lipid peroxidation, which can be considered as a manifestation of prenatal stress syndrome. An increase in the antioxidant potential is an adaptive (stress-restrictive) response that reduces the degree of oxidative stress and prevents damage to cell membranes.